Zepbound (tirzepatide) cost: every price, with and without insurance

Self-pay, Zepbound starts at $299 per 28 days (injection, vial, 2.5 mg). With commercial insurance that covers it, the maker's card can bring a fill down to $25. 7 places with a verified price are compared below over the first 52 weeks.

What you pay, by situation

No insurance
No, the $25 Zepbound card needs commercial insurance. Without insurance you pay Lilly's self-pay price: $299 a fill at 2.5 mg, for vials or the KwikPen.
Savings card with no insurance
Commercial insurance
Yes, if your commercial plan covers the Zepbound pen: you may pay as little as $25 a fill, with savings capped at $100 a month and $1,300 a year.
Savings card with commercial insurance
Medicare
No, the Zepbound savings card excludes Medicare. The Medicare GLP-1 Bridge covers the Zepbound KwikPen for a $50 copay if you qualify.
Savings card with Medicare
Medicaid
No, the Zepbound savings card excludes Medicaid and every other government-funded program.
Savings card with Medicaid

All the card's terms: Zepbound Savings Card. On Medicare: the Medicare GLP-1 Bridge.

Made by: Eli Lilly
Form and how often: Injection, vial: once a week lilly.comInjection, pen: once a week lilly.com
Lowest first 52 weeks: $3,887 at LillyDirect

Self-pay price at every dose

Straight from Eli Lilly's own pharmacy, with no membership. Open a total to see how 52 weeks add up.

Zepbound, injection, vial · once a week

Dose	Medication, per fill	First 52 weeks, all fees
2.5 mg	$299 per 28 days	$3,887 how we got this Medication: 13 × $299 = $3,887 lilly.com Total: $3,887 One fill lasts 28 days, so 52 weeks take 13 fills.
5 mg	$399 per 28 days	$5,187 how we got this Medication: 13 × $399 = $5,187 lilly.com Total: $5,187 One fill lasts 28 days, so 52 weeks take 13 fills.
7.5 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
10 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
12.5 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
15 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.

7.5 mg and up: $449 is for a first fill at that dose or a refill within 45 days. Later refills cost $499 (7.5 mg) or $699 (10 mg and up). Needles and syringes are bought separately.

Fill length: Month is defined as 28-days and 4 single-dose vialslilly.com, Sep 28, 2026

Zepbound, injection, pen · once a week

Dose	Medication, per fill	First 52 weeks, all fees
2.5 mg	$299 per 28 days	$3,887 how we got this Medication: 13 × $299 = $3,887 lilly.com Total: $3,887 One fill lasts 28 days, so 52 weeks take 13 fills.
5 mg	$399 per 28 days	$5,187 how we got this Medication: 13 × $399 = $5,187 lilly.com Total: $5,187 One fill lasts 28 days, so 52 weeks take 13 fills.
7.5 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
10 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
12.5 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.
15 mg	$449 per 28 days	$5,837 how we got this Medication: 13 × $449 = $5,837 lilly.com Total: $5,837 One fill lasts 28 days, so 52 weeks take 13 fills.

KwikPen, one multi-dose pen per fill. 7.5 mg and up: $449 is for a first fill at that dose or a refill within 45 days. Later refills cost $499 (7.5 mg) or $699 (10 mg and up).

Fill length: Month is defined as 28-days and 1 single-patient-use KwikPenlilly.com, Sep 28, 2026

Where to get Zepbound

Sorted by what the first 52 weeks cost at the starting dose, membership and one-time fees included.

1LillyDirectInjection, vial · no membership$3,887first 52 weeksCheck price at LillyDirect (opens LillyDirect's site)
2LillyDirectInjection, pen · no membership$3,887first 52 weeksCheck price at LillyDirect (opens LillyDirect's site)
3PlushCareInjection, vial · membership $19.99 per month ($0 for the first one)$4,235.89first 52 weeksCheck price at PlushCare (opens PlushCare's site)
4WeightWatchers Med+Injection, vial · membership $74 per month ($25 for the first one)$4,726first 52 weeksCheck price at WeightWatchers Med+ (opens WeightWatchers Med+'s site)
5WeightWatchers Med+Injection, pen · membership $74 per month ($25 for the first one)$4,726first 52 weeksCheck price at WeightWatchers Med+ (opens WeightWatchers Med+'s site)
6SesameInjection, vial · membership $99 per month$5,075first 52 weeksCheck price at Sesame (opens Sesame's site)
7SesameInjection, pen · membership $99 per month$5,075first 52 weeksCheck price at Sesame (opens Sesame's site)
8Noom MedInjection, vial · membership $129 per month ($39 for the first one)$5,345first 52 weeksCheck price at Noom Med (opens Noom Med's site)
9RoInjection, pen · membership $149 per month ($39 for the first one)$5,565first 52 weeksCheck price at Ro (opens Ro's site)
10FoundInjection, vial · membership $149 per 28 days$5,824first 52 weeksCheck price at Found (opens Found's site)

Every medication at once: GLP-1 without insurance · ranked by price.

GLPLens compares prices and does not give medical advice. Only a clinician who knows your history can decide whether Zepbound is right for you. Medical disclaimer.