Guides and tools

Everything here quotes an official page: the program, the maker, the FDA label, or CMS.

Paying for it

GLP-1 without insuranceThe cheapest verified brand-name route for each medication
Programs ranked by priceOnline clinics ranked by what 52 weeks cost
Price trapsWhere the headline price and the real cost part ways
Wegovy vs Zepbound costEvery dose, 52 weeks
Wegovy pill vs shot costEvery dose, 52 weeks
TrumpRx pricesEvery TrumpRx GLP-1 price against the maker's own
Price historyThe lowest price of each medication, week by week
Free GLP-1s: patient assistanceNovo Nordisk's program and Lilly Cares
HSA and FSAWhat the IRS rules say, and which programs take HSA money

Choosing a program or pharmacy

Every programWhat each online clinic and maker pharmacy charges
Program reviewsEvery program scored the same way, from its own pages and FDA's
Reader storiesPeople's own accounts: dose, side effects, cost
Cancelling and refundsMinimum terms, refunds, and whether the medication is included
Store pharmaciesWalmart, Costco, CVS, Walgreens, Amazon
Prices by stateWhich programs serve your state, and the table filtered for it
Do you need a prescription?What FDA and the makers say, and where people get one

Insurance and Medicare

Does insurance cover GLP-1s?Federal rules and 20 insurers, in their own words
Medicaid, state by stateWhat each state's own pages say
Savings cardsCan you use the maker's card with your coverage?
Medicare GLP-1 BridgeThe $50 copay, who qualifies, how to get it
Bridge checkerMight you qualify? A quick check against CMS's criteria
Prior authorization lettersTemplates for each approved use, and an appeal letter
Insurance glossaryFormulary, tiers, exception, appeal, defined by HealthCare.gov and Medicare.gov

The medications

What each GLP-1 is approved forQuoted from each FDA label
Side effects comparedRates from each FDA label
Dosing comparedStart, maximum, missed doses
Weight loss resultsWhat each label reports from its trials
Mounjaro vs ZepboundSame tirzepatide, different label and price
Is there still a shortage?FDA's decisions and what they changed for compounded copies
Fake and unapproved productsCounterfeits, research peptides, drops and patches
GLP-1 newsApprovals, prices and rules, dated and sourced
Zepbound costEvery price, with and without insurance
Wegovy costEvery price, with and without insurance
Foundayo costEvery price, with and without insurance
Ozempic costEvery price, with and without insurance
Mounjaro costEvery price, with and without insurance

Health and side effects

A sample GLP-1 meal plan for one week (printable)A week of simple meals built on what the FDA labels, federal dietary guidelines and a 2025 expert advisory say about eating on a GLP-1. Printable PDF.
Can you take a GLP-1 while breastfeeding? What each label saysWegovy, Ozempic, Zepbound, Mounjaro and Foundayo while breastfeeding: what each FDA label says, drug by drug, and what it leaves open.
Compounded GLP-1 doses vs label doses: units, mg and errorsWegovy and Zepbound label doses in milligrams, why compounded semaglutide and tirzepatide doses in units lead to errors, and what the FDA has seen.
Compounded semaglutide and tirzepatide: what the FDA saysWhat compounding is, how 503A pharmacies differ from 503B outsourcing facilities, what changed when the shortages ended, and the FDA's safety warnings.
Do GLP-1 drugs affect sex drive? What studies and labels showWhat surveys and studies report about libido, erectile dysfunction and testosterone on semaglutide and other GLP-1s, and what the FDA labels list.
Drinking alcohol on a GLP-1: what labels and research sayGLP-1 labels do not mention drinking. What their pancreatitis and low blood sugar warnings mean if you drink, and what the alcohol use disorder trials found.
GLP-1 constipation: how common it is and what helpsConstipation rates on Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro from the FDA labels, what NIH suggests, and the warning signs to call about.
GLP-1 diarrhea: how common it is, how long it lasts, what helpsDiarrhea rates on Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro from the FDA labels, the placebo rates beside them, NIH self-care and when to call.
GLP-1 drugs and suicidal thoughts: what the FDA and labels say nowWhy the FDA had the suicidal-thoughts warning taken off Wegovy and Zepbound, what UK and EU regulators found, and what labels say about antidepressants.
GLP-1 drugs still in trials (retatrutide and others)Retatrutide, CagriSema, MariTide, survodutide and zenagamtide: what trial registrations and the makers say, and why none can be bought legally today.
GLP-1 fatigue: how common it is and what to checkFatigue rates on Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro from the FDA labels, other causes the labels point to, and when tiredness needs a call.
GLP-1 hair loss: how common it is and what the labels sayHair loss rates for Zepbound, Wegovy and Foundayo from the FDA labels, including the gap between women and men, and what MedlinePlus says about shedding.
GLP-1 microdosing: what it means and what the labels sayWhat GLP-1 microdosing means, why no FDA label has a microdose schedule, the approved starting doses, and what the FDA says about compounded doses.
GLP-1 nausea: how common it is, how long it lasts, what helpsNausea rates for Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro from each FDA label, when it eases, NIH self-care tips and when to call a doctor.
GLP-1 research overview: the main trial behind each approved useOne line per FDA-approved use of Wegovy, Zepbound, Foundayo, Ozempic and Mounjaro: the trial behind it and its headline result, with the published abstract.
GLP-1s, muscle and bone: what the trials measuredHow much lean mass people lost on tirzepatide and semaglutide in trial scans, what a 2026 review found for bone, and NIH advice on protein and strength work.
How GLP-1 weight loss unfolds over time: what the trials showWhen weight loss on Wegovy and Zepbound tends to slow and level off, what the long trials found at two to four years, and what happened when people stopped.
How to find a GLP-1 clinical trial for weight lossSearch ClinicalTrials.gov for GLP-1 obesity studies, read a study record, understand trial phases and placebo groups, and know what to ask before you join.
Ozempic and asthma: what the 2026 study found and what it did notThe semaglutide asthma finding presented in September 2026, the earlier published study behind it, and why neither makes Ozempic or Wegovy an asthma drug.
Ozempic face: what it is and what the research saysWhat doctors mean by Ozempic face, why rapid weight loss changes the face, what the labels do and do not list, and what dermatology groups say about it.
Restarting a GLP-1 after a break: what each label saysMissed-dose and restart rules from the Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro labels, why a restart can mean a lower dose, and what to check on cost.
Semaglutide and lifespan: what the mouse study foundA Nature study found semaglutide extended the lives of old female mice. What was tested, what the numbers were, and why it says nothing yet about people.
Sulfur burps on a GLP-1: what the labels call it and what helpsThe FDA labels list burping as eructation. Rates for Zepbound, Wegovy, Foundayo, Ozempic and Mounjaro, NIH tips for belching, and when to call.
Tirzepatide vs semaglutide: the head-to-head trial and the labelsWhat SURMOUNT-5 found when tirzepatide and semaglutide were compared directly, how the Zepbound and Wegovy labels differ, and where to compare prices.
What is semaglutide? Brands, forms and approved usesSemaglutide is the medicine inside Wegovy, Ozempic and Rybelsus. What the FDA labels say it does, what each brand is approved for, and how it is taken.
What is tirzepatide? Zepbound, Mounjaro and how it worksTirzepatide is the medicine in Zepbound and Mounjaro. What the FDA labels say it does, what each brand is approved for and how it is taken.
What to eat on a GLP-1: a diet guide from official sourcesGLP-1 labels say to use the drugs with a reduced-calorie diet and more activity. What NIDDK, the Dietary Guidelines and a 2025 expert advisory say to eat.
Zepbound for fatty liver (MASH): trial results and approval statusTirzepatide's phase 2 SYNERGY-NASH results, why Zepbound is not approved for MASH while Wegovy is, and what that means for insurance and Medicare.
Zepbound for heart failure (HFpEF): the SUMMIT trial and the labelWhat the SUMMIT trial of tirzepatide in heart failure with preserved ejection fraction found, why Zepbound's label has no heart failure use, and coverage.

Costs

Can you use TrumpRx with insurance or Medicare?TrumpRx GLP-1 prices are cash prices. What its terms ask of people with a health plan, Medicare or Medicaid, and when the Medicare GLP-1 Bridge costs less.
Compounded vs brand-name GLP-1 prices: what each really costsBrand-name Wegovy, Zepbound and Foundayo self-pay prices next to compounded plans that publish prices, the fees behind the headline, and why we list brand only.
GLP-1 price changes in 2025 and 2026: a dated recordOfficial Wegovy, Zepbound and Foundayo price announcements since late 2025, with dates: maker self-pay cuts, TrumpRx launch prices and the Medicare Bridge.
Mounjaro patient assistance: Lilly Cares and other ways to payCan you get Mounjaro free? What Lilly says about Lilly Cares, what could not be confirmed, and the Mounjaro savings card and self-pay prices.
Wegovy patient assistance: what Novo Nordisk's program saysCan you get Wegovy free? What Novo Nordisk's Patient Assistance Program page says, what it leaves unclear about Wegovy, and the cheapest verified routes.
What Hims and Hers GLP-1 programs cost in 2026Hims and Hers GLP-1 cost: a $39 first month, then $149 a month for membership, plus medication from $149 a month. What is included and the FDA letter status.
Zepbound patient assistance: Lilly Cares and cheaper routesIs Zepbound free through Lilly Cares? What Lilly's own pages say, what could not be confirmed, and the lowest Zepbound prices you can verify today.

Insurance

BMI dropped on a GLP-1? What insurance renewal actually requiresYour weight came down and the prior authorization is up for renewal. What published renewal rules measure, how long approvals last, and what to send.
Does your employer cover GLP-1s for weight loss? What surveys showAbout one in five large employers cover GLP-1s for weight loss, per KFF. What insurers say about employer choice, and how to check your own plan.
Insurance dropped your GLP-1 coverage? What to do nextYour plan stopped paying for Wegovy or Zepbound. How to find out what changed, your appeal and exception rights, 2026 changes insurers posted, and cash routes.

Comparisons

Wegovy vs Zepbound: 5-year cost at today's self-pay pricesYear 1 and a five-year projection for Wegovy and Zepbound at the makers' own cash prices, dose path by dose path. Later years assume today's prices.

Everything else

Amazon One Medical GLP-1 care: visit fees, drug prices and statesAmazon One Medical's pay-per-visit GLP-1 care: $39 message or $59 video visits in 48 states and DC, medicine billed separately, and what Medicare patients pay.
Berberine and the pink salt trick are not GLP-1 drugsBerberine is called nature's Ozempic and a pink salt drink is sold as a diet trick. What NIH, FDA and FTC pages say, and where real GLP-1 drugs come from.
Can you get a GLP-1 for PCOS? What labels and insurers sayNo GLP-1 is FDA-approved for PCOS. How people with PCOS can still qualify through approved uses like weight management, what insurers say, and label cautions.
GLP-1 patches and "GLP-1" supplements are not GLP-1 drugsPatches, gummies and drops sold with GLP-1 in the name are not prescription GLP-1 medicines. What the FDA and FTC say, and how to spot these products.
GLP-1 statistics 2026: prices, Medicare, Medicaid and shortagesKey US GLP-1 numbers with an official source for each: brand self-pay prices, the Medicare GLP-1 Bridge, Medicaid coverage by state and FDA shortage dates.
History of GLP-1 drugs: from a fish gene to weekly shotsHow a hormone found through anglerfish genes and Gila monster venom became Ozempic, Wegovy and Zepbound, with every FDA approval date from Drugs@FDA.
How many Americans take GLP-1 drugs? What the surveys sayAbout one in eight US adults said they were taking a GLP-1 in a late-2025 KFF poll. What that poll and a 2026 Gallup survey measured, and when they ran.
How to switch GLP-1 programs without a gap in treatmentChanging online GLP-1 programs: get the new prescription before you cancel, what labels say about missed doses, and each program's cancellation cutoff.
Is Push Health legit? How it works and what it costsPush Health links you with independent prescribers and sends prescriptions to your pharmacy. How it works, what you pay, which GLP-1s it lists, what we checked.
Is there a generic Ozempic? What FDA records show in 2026No FDA-approved generic semaglutide is on the market. What the FDA Orange Book lists for Ozempic and Wegovy patents, and why compounded copies are not generics.
Novo Nordisk now goes by Novo: what it means for Wegovy patientsThe maker of Wegovy and Ozempic now calls itself Novo day to day. What its announcement says, what stays the same, and where Wegovy prices stand.
Who writes GLP-1 rankings, and how to read oneMany best GLP-1 program lists earn a commission or come from a program itself. What FTC rules require, and six checks before you trust a ranking.
Why GLP-1 drugs cost more in the US than abroadWhat federal data say about US brand-drug prices compared with other rich countries, why Wegovy and Zepbound list prices ran so high, and what has changed.